Calling all 20-somethings! A roundup of nostalgic anime from the 2000s to the 2010s

D·N·A² ~That Someone’s Something I Lost Somewhere~

Trivia about DNA²: Aitsu no Aitsu I Lost Somewhere

The anime “D·N·A²: Dokoka de Nakushita Aitsu no Aitsu” is based on Masakazu Katsura’s manga and aired in 1994.

It has a strong sci-fi storyline in which Karin Aoi, a DNA operator, travels from the future to modify the DNA of the protagonist, Junta Momonari.

Despite its sci-fi elements, it also unfolds as a romantic comedy, and that contrast drew attention.

It’s also remembered for detailed tidbits, such as having theme songs performed by L’Arc~en~Ciel and Sharan Q just before their big break.

Neon Genesis Evangelion

Premiering in 1995, the anime Neon Genesis Evangelion tells the story of boys and girls who pilot giant humanoid weapons called Evangelions to fight mysterious enemies known as Angels.

Far from being just a sci-fi robot anime, it delves deeply into psychological portrayals and philosophical themes, sparking a social phenomenon that extended beyond anime fans of the time.

Its stylish visuals, shocking storyline, and distinctive characters have combined to earn it enduring popularity.

In addition to the TV series, its extensive media expansion—including theatrical films and a manga adaptation—is also part of its appeal.

Yu-Gi-Oh!

[Yu-Gi-Oh!] The results of opening 50 discontinued packs and sending them for grading are insane. [Early Premium Pack 1 / ARS Grading]

The 1998 anime often considered the origin of the series, Yu-Gi-Oh!, is a work whose appeal lies in its horror-tinged atmosphere from the early manga and its thrilling developments.

After the protagonist, Yugi Mutou, solves the ancient Egyptian Millennium Puzzle, a second persona emerges, who judges evil through Shadow Games and resolves incidents.

Not only Yugi’s friends but also the villains are strikingly unique, and their relationships further heighten the drama.

The in-story card game, Magic and Wizards, became the basis for Duel Monsters, which then expanded and led to everything that followed—making this a work that can truly be called the beginning of a legend.

Ojamajo Doremi

[Official] Ojamajo Doremi Episode 1: "I’m Doremi! I’m Going to Be a Witch Apprentice!!"

I bet there are quite a few people who love singing the opening theme at karaoke! The magical girl anime Ojamajo Doremi began airing in 1999.

Its popularity comes from stories full of humor, tears, and heartfelt humanity.

That spell you can’t help but chant yourself is probably a nostalgic memory too.

In 2020, the 20th-anniversary film Looking for Magical Doremi was also released.

It’s a story that especially resonates with those who watched Ojamajo Doremi as children.

Nodame Cantabile

Nodame Cantabile Opening

Many people in their 20s today may have watched Nodame Cantabile when they were in elementary school and, because of it, became interested in classical music or even started playing instruments themselves.

Based on Tomoko Ninomiya’s hugely popular manga, the animated series Nodame Cantabile aired on Fuji TV’s Noitamina block from 2007 to 2010 across three seasons, and became a major hit centered on classical music.

It’s also a rare case where both the live-action and the anime adaptations were successful.

Despite its classical music theme, the show is anything but stuffy: from the protagonist Nodame on down, the wonderfully eccentric characters are irresistibly charming, and the series brilliantly lets you learn about classical music while laughing out loud.

It’s enjoyable for all ages, so if you’ve just become interested now, be sure to check it out!

The Tatami Galaxy

The Tatami Time Machine Blues - Official Trailer (60 seconds)

An anime based on Tomihiko Morimi’s novel, it portrays the chaotic everyday lives of university students in Kyoto.

It weaves in plenty of uniquely student-like bluffing and inner conflict, and with real Kyoto place names popping up, it’s a work that will resonate especially with those who spent their college years in the city.

A major feature is its incorporation of parallel worlds, letting viewers enjoy how the protagonist’s story changes depending on the clubs or organizations he chooses.

It’s also packed with animation-specific charms, from rapid-fire, breathless dialogue to the momentum of its distinctive art style.

Rurouni Kenshin: Meiji Swordsman Romantic Story

TV anime Rurouni Kenshin: Meiji Swordsman Romantic Story - First Teaser PV

Rurouni Kenshin: Meiji Swordsman Romantic Story is a work that portrays how a swordsman said to be the strongest at the end of the Edo period lived on in the Meiji era.

It depicts the protagonist, Kenshin Himura—once feared as the manslayer Battōsai—taking a vow never to kill and helping those in need.

The story is compelling, from Kenshin’s past and inner turmoil to his interactions with a cast of fascinating allies and his ferocious battles with arch-enemies.

The intense action set in a world like a period drama stirred the hearts of viewers.

It is a long‑loved series that helped support Shonen Jump’s golden age.