Lovely commercial jingle

[Sedes Commercials] Popular and Historic TV Ads Summary [2026]

Editor-in-Chief, RAG MUSICHane Keisuke
Editor-in-chief of RAG MUSIC. JFC-certified fact-checker. After working in a music studio and handling wedding sound, joined the RAG MUSIC editorial team in 2016. Experienced with a variety of instruments: marching band in elementary school, clarinet in junior high school wind ensemble, and drums in a band from high school onward. Drawing on my own musical activities and the experience gained through my work, I produce daily articles, including various song introductions, features on music festivals around the country, and live reports. In music, I enjoy not only rock from Japan and abroad but, lately, a wide range of J-pop as well.

Have you ever heard the phrase “If pain strikes, take Sedes right away”? It’s the line from the commercials for Sedes, a product sold by Shionogi Healthcare.

Sedes is effective mainly for menstrual cramps and headaches, as well as neuralgia and reducing fever—many of you have probably relied on it at some point.

In this article, we’ll introduce all the Sedes commercials that have aired so far.

Some of them became a hot topic for their star-studded casts, so be sure to pay attention to the performers as you watch.

[Sedes Commercials] Popular and Historical Commercials Summary [2026] (1–10)

Shionogi Healthcare New Sedes “Alien Appearance” VersionMizuki Yamamoto

Shionogi Healthcare New Sedes Commercial (2022)

In the 2022 New Sedes commercial featuring Mizuki Yamamoto, it highlights that Sedes is a pain reliever that’s easy for anyone to use.

It carefully introduces each feature, such as the easy-to-open packaging and a QR code linking to a translation page that’s understandable for people from overseas.

It’s a commercial that clearly conveys you can use it with peace of mind.

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Shionogi Healthcare New SEDES Tablets: “Watch Out for Throbbing and Mizuki” VersionMizuki Yamamoto, Mio Imada

Shionogi Healthcare | New Sedes Tablets TV Commercial: “Beware of Throbbing Mizuki”

This is a Sedes commercial featuring Zukizuki Mizuki, played by Mizuki Yamamoto.

Although Zukizuki Mizuki is portrayed as a devil representing the cause of pain, fans of Yamamoto have also called her an “angel!” The way she says “Zuki zuki zuki~” is adorable.

The junior colleague appearing alongside Mizuki Yamamoto is the rising actress Mio Imada.

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Shionogi Healthcare New SEDES Tablets 1990 CommercialYoko Oginome

Nostalgic commercial: Shionogi Pharmaceutical – New Sedes Tablets (Yoko Oginome), June 1990

The sound logo from the Sedes commercial—“If pain strikes, take Sedes right away”—has actually been around since way back then! And not only that single line, but there was more that followed… I bet many people didn’t know that.

Even back then, they emphasized how quickly and effectively it works.

The final line, “If pain strikes, take Sedes,” is so catchy it makes you want to hum it over and over!

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[Sedes Commercials] Popular and Historic Commercial Compilation [2026] (11–20)

Shionogi Healthcare SEDES 2009Anju Suzuki

[CM] Shionogi Pharmaceutical SEDES Anju Suzuki (2009)

This commercial looks back on the history of Sedes and Shionogi Pharmaceutical in confronting pain, conveying the confidence born from that experience.

The visuals alternate between the Sedes package and people suffering from pain, and finally transition to a smiling photo to evoke a sense of reassurance.

The way Anju Suzuki explains with a smile and the variety of products also convey an attitude of standing by the user.

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Shionogi Healthcare Sedes Cure: “Getting Ready” versionNatsuki Harada

Shionogi Pharmaceutical Sedes Cure Getting Ready Version 2005 TV Commercial

This commercial conveys the desire for people to incorporate Sedesecure into their everyday routines and live with peace of mind.

It cheerfully portrays Natsuki Harada getting ready for a date, including little mishaps like a bento or makeup mistakes.

She handles her anxious preparations with a smile, and by keeping Sedesecure on hand for just in case, it also gives an impression of trustworthiness.

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Shionogi Healthcare Sedes High Protect “Quintet Formula” EditionMizuki Yamamoto

[Japanese Advertisement] Mizuki Yamamoto, SEDES High, Japanese expressions in the commercial, “I want to get better quickly. Take SEDES right away♪” Includes Japanese and Korean subtitles. TV commercial starring Mizuki Yamamoto.

This commercial highlights the high effectiveness of Sedes High Protect, which delivers both relief from severe headaches and protection for the stomach.

It powerfully conveys both its strong efficacy and peace of mind by combining multiple pain-relieving ingredients with components that protect the stomach.

With Mizuki Yamamoto providing a stylish explanation, it also evokes the impression that the effects are felt quickly.

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Shionogi Healthcare Sedes First Smile Ambassador “Travel” VersionSanma Akashiya

Nice commercial: Shionogi Pharmaceutical – Sedes First – Sanma Akashiya – Travel Edition

In one of the Sedes series commercials, Sedes First, the featured performer is Sanma Akashiya.

The word “First” really suits Sanma, who’s known for talking a lot in rapid-fire Kansai dialect (lol).

The ad even shows his “first-ness” by having him arrive at the ryokan before the protagonists, resulting in a commercial filled with Sanma’s trademark humor.

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