[Sedes Commercials] Popular and Historic TV Ads Summary [2026]
Have you ever heard the phrase “If pain strikes, take Sedes right away”? It’s the line from the commercials for Sedes, a product sold by Shionogi Healthcare.
Sedes is effective mainly for menstrual cramps and headaches, as well as neuralgia and reducing fever—many of you have probably relied on it at some point.
In this article, we’ll introduce all the Sedes commercials that have aired so far.
Some of them became a hot topic for their star-studded casts, so be sure to pay attention to the performers as you watch.
- Shionogi commercials: A collection of ads for SEDES and other medicines
- [Nostalgic Commercials] A compilation of commercials that aired in the Showa era
- [Cecile Commercials] Popular and Historical Commercials Compilation [2026]
- Nostalgic commercials from the 2000s: revisiting ads that left a lasting impression
- [April 2026] Summary of the Latest Trending Commercial Songs
- [Reve 21 Commercials] Popular and All-Time Commercials Summary [2026]
- [AXA Direct Commercials] Popular and All-Time Commercials Summary [2026]
- [April 2026] Introducing the latest commercials all at once! A roundup of noteworthy ads
- A Shiseido commercial. A recommended ad featuring a lineup of popular actresses.
- A commercial featuring Hana Sugisaki. Showcasing everything from the latest ads to her past appearances in one go.
- A must-see for people in their 30s and 40s! A roundup of nostalgic 1990s commercial jingles
- Commercial songs from the 70s. Nostalgic TV commercial jingles.
- [Mercedes-Benz Commercial] Popular CM Songs. Historical CM Tracks [2026]
[Sedes Commercials] Popular and Historical Commercials Summary [2026] (1–10)
Shionogi Healthcare New SEDES Tablets: “Watch Out for Throbbing and Mizuki” VersionMizuki Yamamoto, Mio Imada
This is a Sedes commercial featuring Zukizuki Mizuki, played by Mizuki Yamamoto.
Although Zukizuki Mizuki is portrayed as a devil representing the cause of pain, fans of Yamamoto have also called her an “angel!” The way she says “Zuki zuki zuki~” is adorable.
The junior colleague appearing alongside Mizuki Yamamoto is the rising actress Mio Imada.
Shionogi Healthcare SEDES 2009Anju Suzuki
This commercial looks back on the history of Sedes and Shionogi Pharmaceutical in confronting pain, conveying the confidence born from that experience.
The visuals alternate between the Sedes package and people suffering from pain, and finally transition to a smiling photo to evoke a sense of reassurance.
The way Anju Suzuki explains with a smile and the variety of products also convey an attitude of standing by the user.
Shionogi Healthcare Sedes Cure: “Getting Ready” versionNatsuki Harada
This commercial conveys the desire for people to incorporate Sedesecure into their everyday routines and live with peace of mind.
It cheerfully portrays Natsuki Harada getting ready for a date, including little mishaps like a bento or makeup mistakes.
She handles her anxious preparations with a smile, and by keeping Sedesecure on hand for just in case, it also gives an impression of trustworthiness.
[Sedes Commercials] Popular and Historic Commercial Compilation [2026] (11–20)
Shionogi Healthcare Sedes High Protect “Quintet Formula” EditionMizuki Yamamoto
This commercial highlights the high effectiveness of Sedes High Protect, which delivers both relief from severe headaches and protection for the stomach.
It powerfully conveys both its strong efficacy and peace of mind by combining multiple pain-relieving ingredients with components that protect the stomach.
With Mizuki Yamamoto providing a stylish explanation, it also evokes the impression that the effects are felt quickly.
Shionogi Healthcare Sedes High 1994Vanessa Williams
It’s a commercial that seems to convey the effectiveness and reassurance of Sedes through Vanessa Williams’s powerful singing.
Structured like a music video that ends with an announcement for Sedes, the visuals also convey a sense of warmth.
The song that powerfully communicates the product’s reliability is “Save The Best For Last.” It’s a track where a powerful vocal soars over a gentle sound, and that strength itself becomes a point that inspires a feeling of reassurance.
Shionogi Healthcare Sedes A Tablets TV CommercialNoriko Matsumoto
It’s a commercial notable for its beautiful, choir-like music.
It has a simple structure where the key selling points are narrated over the BGM, and Noriko Matsumoto appears in it.
At the end of the ad, a sound logo different from the familiar one we still often hear today is used, which might actually feel fresh to generations who don’t know that era.
It seems Sedes was already casting popular women who appealed to young female audiences back then.
Shionogi Healthcare Sedes V 2006 CommercialEmiri Henmi
In this commercial, a woman getting a shoulder massage keeps requesting, “A little higher, a little higher,” and ultimately ends up having her head massaged.
If you suffer from headaches caused by shoulder or neck stiffness, you’ll probably relate and think, “I know that feeling!” The ad highlights that Sedes is effective for shoulder stiffness pain and headaches, and it’s clearly designed to appeal directly to people experiencing these target symptoms.