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[Sedes Commercials] Popular and Historic TV Ads Summary [2026]

Have you ever heard the phrase “If pain strikes, take Sedes right away”? It’s the line from the commercials for Sedes, a product sold by Shionogi Healthcare.

Sedes is effective mainly for menstrual cramps and headaches, as well as neuralgia and reducing fever—many of you have probably relied on it at some point.

In this article, we’ll introduce all the Sedes commercials that have aired so far.

Some of them became a hot topic for their star-studded casts, so be sure to pay attention to the performers as you watch.

[Sedes Commercials] Popular and Historic Commercial Compilation [2026] (11–20)

Shionogi Healthcare Sedes First Smile Ambassador “Travel” VersionSanma Akashiya

Nice commercial: Shionogi Pharmaceutical – Sedes First – Sanma Akashiya – Travel Edition

In one of the Sedes series commercials, Sedes First, the featured performer is Sanma Akashiya.

The word “First” really suits Sanma, who’s known for talking a lot in rapid-fire Kansai dialect (lol).

The ad even shows his “first-ness” by having him arrive at the ryokan before the protagonists, resulting in a commercial filled with Sanma’s trademark humor.

Shionogi Healthcare New SEDES Tablets 1990 CommercialYoko Oginome

Nostalgic commercial: Shionogi Pharmaceutical – New Sedes Tablets (Yoko Oginome), June 1990

The sound logo from the Sedes commercial—“If pain strikes, take Sedes right away”—has actually been around since way back then! And not only that single line, but there was more that followed… I bet many people didn’t know that.

Even back then, they emphasized how quickly and effectively it works.

The final line, “If pain strikes, take Sedes,” is so catchy it makes you want to hum it over and over!

Shionogi Healthcare New Sedes Tablets “Flower Shop” VersionAsaka Seto

Shionogi Pharmaceutical New Sedes Tablets TV Commercial

This is the 2005 “Flower Shop” commercial for the new Sedes featuring Asaka Seto.

It begins with a scene where Seto, working at a flower shop, feels a headache coming on.

Thanks to Sedes, the pain subsides, and she’s able to continue working energetically.

The ad conveys the shock of a headache’s onset and the refreshing feeling after the pain eases—something many viewers can likely relate to.

Shionogi Healthcare Sedes High G “My Deciding Factor” VersionHaruna Kawaguchi

“My Deciding Factor” Cedes High G Version

This commercial promotes how Sedes High G firmly supports everyone’s desire to quickly relieve headaches.

It powerfully conveys the high effectiveness of having the same ingredients and the same formulation as prescription medicine.

Haruna Kawaguchi’s direct gaze at the viewer and the way the people around her break into smiles evoke the strong efficacy of the product and the relief of symptoms.

Shionogi Healthcare Sedes High “RELEASE” EditionMizuki Yamamoto

[Japanese Advertisement] Mizuki Yamamoto, Sedes High, Japanese expressions in the commercial, “Works fast and well.” Includes Japanese and Korean subtitles. TV commercial featuring Mizuki Yamamoto.

This commercial features Mizuki Yamamoto giving a straightforward explanation of how Sedes works to relieve pain.

While gazing at the Sedes package, she explains which ingredients work and how, and conveys how that leads to a smile.

The light, eye-catching animation that makes use of the Sedes packaging is also memorable, and the cheerful atmosphere evokes the easing of pain and anxiety.

Shionogi Healthcare Sedes High “Mitsuki Begging” VersionMizuki Yamamoto

[Mizuki Yamamoto] Sedes High Commercial – “Begging Mizuki” Compilation

This is a commercial that highlights Mizuuki Yamamoto’s cuteness by showing her asking for Sedes High in various situations.

By depicting her casually begging for it in everyday moments, it also conveys the desire for people to incorporate Sedes into their daily lives with ease.

Because the content is simply about wanting Sedes, it leaves the impression that its effectiveness and reassuring quality also come through.

[Sedes Commercials] Popular and Historical Commercials Summary [2026] (21–30)

Shionogi Healthcare Sedes High “The answer is High” versionMinako Tanaka

This is a commercial that recommends Sedes High when you want to quickly relieve a headache, and it also introduces its ingredients and effects.

It highlights which ingredients lead to which effects, accompanied by bright, clear visuals.

The way Minako Tanaka’s expression changes from troubled to a radiant smile also gives the impression that the product is effective.