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[Sedes Commercials] Popular and Historic TV Ads Summary [2026]

Have you ever heard the phrase “If pain strikes, take Sedes right away”? It’s the line from the commercials for Sedes, a product sold by Shionogi Healthcare.

Sedes is effective mainly for menstrual cramps and headaches, as well as neuralgia and reducing fever—many of you have probably relied on it at some point.

In this article, we’ll introduce all the Sedes commercials that have aired so far.

Some of them became a hot topic for their star-studded casts, so be sure to pay attention to the performers as you watch.

[Sedes Commercials] Popular and Historic Commercial Compilation [2026] (11–20)

Shionogi Healthcare Sedes A Tablets TV CommercialNoriko Matsumoto

Shionogi Pharmaceutical Sedes A Tablets TV Commercial

It’s a commercial notable for its beautiful, choir-like music.

It has a simple structure where the key selling points are narrated over the BGM, and Noriko Matsumoto appears in it.

At the end of the ad, a sound logo different from the familiar one we still often hear today is used, which might actually feel fresh to generations who don’t know that era.

It seems Sedes was already casting popular women who appealed to young female audiences back then.

Shionogi Healthcare Sedes V 2006 CommercialEmiri Henmi

Shionogi Pharmaceutical 'Sedes V' commercial (2006)

In this commercial, a woman getting a shoulder massage keeps requesting, “A little higher, a little higher,” and ultimately ends up having her head massaged.

If you suffer from headaches caused by shoulder or neck stiffness, you’ll probably relate and think, “I know that feeling!” The ad highlights that Sedes is effective for shoulder stiffness pain and headaches, and it’s clearly designed to appeal directly to people experiencing these target symptoms.

Shionogi Healthcare New Sedes Tablets “Flower Shop” VersionAsaka Seto

Shionogi Pharmaceutical New Sedes Tablets TV Commercial

This is the 2005 “Flower Shop” commercial for the new Sedes featuring Asaka Seto.

It begins with a scene where Seto, working at a flower shop, feels a headache coming on.

Thanks to Sedes, the pain subsides, and she’s able to continue working energetically.

The ad conveys the shock of a headache’s onset and the refreshing feeling after the pain eases—something many viewers can likely relate to.

Shionogi Healthcare Sedes High G “My Deciding Factor” VersionHaruna Kawaguchi

“My Deciding Factor” Cedes High G Version

This commercial promotes how Sedes High G firmly supports everyone’s desire to quickly relieve headaches.

It powerfully conveys the high effectiveness of having the same ingredients and the same formulation as prescription medicine.

Haruna Kawaguchi’s direct gaze at the viewer and the way the people around her break into smiles evoke the strong efficacy of the product and the relief of symptoms.

Shionogi Healthcare New SEDES 2003Asaka Seto

SEDES commercial 2003

Headaches can strike suddenly at the most ordinary moments, and their abrupt onset can really be a problem.

This commercial highlights how Sedes is especially useful in those critical moments—easy to use and ready to relieve your troubles.

It portrays Asaka Seto suffering from a sudden headache just before a presentation, then resolving it with Sedes, effectively conveying its potency.

The change from her pained expression to the bright, confident look after her successful presentation also evokes a sense of reassurance and trust.

Shionogi Healthcare Sedes High “Mitsuki Begging” VersionMizuki Yamamoto

[Mizuki Yamamoto] Sedes High Commercial – “Begging Mizuki” Compilation

This is a commercial that highlights Mizuuki Yamamoto’s cuteness by showing her asking for Sedes High in various situations.

By depicting her casually begging for it in everyday moments, it also conveys the desire for people to incorporate Sedes into their daily lives with ease.

Because the content is simply about wanting Sedes, it leaves the impression that its effectiveness and reassuring quality also come through.

[Sedes Commercials] Popular and Historical Commercials Summary [2026] (21–30)

Shionogi Healthcare Sedes A Tablets TV Commercial

Shionogi Pharmaceutical Sedes A Tablets

This is a fairly early commercial for Sedes.

Its composition is striking, featuring a simple yet essential narration condensed into the line: “Two tablets when it hurts—I will protect you.” In recent commercials, there are often various stylistic flourishes, but ads from this era aim to convey the message straightforwardly, which makes them refreshing to watch!