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[Sedes Commercials] Popular and Historic TV Ads Summary [2026]

[Sedes Commercials] Popular and Historic TV Ads Summary [2026]

Last updated:2025/10/8

Editor-in-Chief, RAG MUSICHane Keisuke
Editor-in-chief of RAG MUSIC. JFC-certified fact-checker. After working in a music studio and handling wedding sound, joined the RAG MUSIC editorial team in 2016. Experienced with a variety of instruments: marching band in elementary school, clarinet in junior high school wind ensemble, and drums in a band from high school onward. Drawing on my own musical activities and the experience gained through my work, I produce daily articles, including various song introductions, features on music festivals around the country, and live reports. In music, I enjoy not only rock from Japan and abroad but, lately, a wide range of J-pop as well.

Have you ever heard the phrase “If pain strikes, take Sedes right away”? It’s the line from the commercials for Sedes, a product sold by Shionogi Healthcare.

Sedes is effective mainly for menstrual cramps and headaches, as well as neuralgia and reducing fever—many of you have probably relied on it at some point.

In this article, we’ll introduce all the Sedes commercials that have aired so far.

Some of them became a hot topic for their star-studded casts, so be sure to pay attention to the performers as you watch.

[Sedes Commercials] Popular and Historical Commercials Summary [2026] (1–10)

Shionogi Healthcare Sedes High Series ‘My Deciding Factor’ EditionHaruna Kawaguchi

Sedes High Series TV Commercial: “My Deciding Factor”

In the Sedes High Series commercial “My Deciding Factor,” the ad highlights Sedes High’s strength: it contains the same active ingredients in the same amounts as prescription pain relievers.

Featuring Haruna Kawaguchi, her poised, confident delivery suggests you can expect strong effectiveness.

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Shionogi Healthcare New Sedes Tablets: “Dress” VersionMizuki Yamamoto

[Mizuki Yamamoto] Shionogi Pharmaceutical New Sedes Tablets “Dress” Version

In this Cedes commercial featuring fashion model Mizuki Yamamoto, she shows off a glamorous model walk wearing a blue dress—the package color of Cedes.

Accompanied by light, rhythmic background music reminiscent of a fashion show, the direction clearly targets young women.

It concludes by displaying a logo and tagline designed to evoke a fashion magazine.

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Shionogi Healthcare Sedes High 1994Vanessa Williams

SEDES commercial

It’s a commercial that seems to convey the effectiveness and reassurance of Sedes through Vanessa Williams’s powerful singing.

Structured like a music video that ends with an announcement for Sedes, the visuals also convey a sense of warmth.

The song that powerfully communicates the product’s reliability is “Save The Best For Last.” It’s a track where a powerful vocal soars over a gentle sound, and that strength itself becomes a point that inspires a feeling of reassurance.

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Shionogi Healthcare Sedes: ‘Fast relief for pain. Sedes High Series’ / ‘The pain professionals. Sedes brand’Haruna Kawaguchi

Haruna Kawaguchi descends to the “ground” with a radiant expression in Shionogi Healthcare’s new SEDES commercial

This is a commercial featuring Haruna Kawaguchi introducing the effectiveness of the Sedes High series.

The standout point is its fantastical world, whose grand and powerful atmosphere conveys both the high efficacy of Sedes and its reliability.

The way the background gradually brightens seems to suggest an image of pain being relieved and one’s field of vision opening up.

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Shionogi Healthcare “SEDES High TV Commercial”Mizuki Yamamoto

CM Shionogi Pharmaceutical Sedes High '2014A' Mizuki Yamamoto

This commercial features Mizuki Yamamoto dressed in a silver dress.

It’s crafted like footage from a fashion shoot, letting you fully appreciate her charm as a fashion model.

Not only is she beautiful, but the way she strikes confident poses is likely very appealing even from a woman’s perspective.

The familiar sound logo has also been stylishly rearranged.

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Shionogi Healthcare SEDES “Children’s Headache Project Begins” EditionHaruna Kawaguchi

"Children's Headache Project, Launch" Version (60 seconds)

This commercial presents the fact that children, just like adults, suffer from headaches, and conveys the message of supporting their struggles.

It is a promotional ad for Shionogi Healthcare’s Children’s Headache Project, and Haruna Kawaguchi’s gentle expressions as she talks with and cares for the children are particularly striking.

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Shionogi Healthcare SEDES High Protect 2022 TV CommercialMizuki Yamamoto

[Mizuki Yamamoto] Shionogi Healthcare SEDES High Protect Commercial (2022)

Mizuki Yamamoto appeared in the 2022 commercial for Sedes High Protect.

In it, Yamamoto speaks for those who think, “I want a painkiller that works well, but I’m worried about the impact on my stomach,” and introduces Sedes High Protect.

The ad highlights that, with five active ingredients, it offers a friendly approach to headaches while also being gentle on the stomach.

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