![[Sedes Commercials] Popular and Historic TV Ads Summary [2026]](https://i.ytimg.com/vi_webp/fcKMHdsT4_Y/maxresdefault.webp)
[Sedes Commercials] Popular and Historic TV Ads Summary [2026]
Have you ever heard the phrase “If pain strikes, take Sedes right away”? It’s the line from the commercials for Sedes, a product sold by Shionogi Healthcare.
Sedes is effective mainly for menstrual cramps and headaches, as well as neuralgia and reducing fever—many of you have probably relied on it at some point.
In this article, we’ll introduce all the Sedes commercials that have aired so far.
Some of them became a hot topic for their star-studded casts, so be sure to pay attention to the performers as you watch.
[Sedes Commercials] Popular and Historical Commercials Summary [2026] (1–10)
Shionogi Healthcare Sedes High Series ‘My Deciding Factor’ EditionHaruna Kawaguchi
In the Sedes High Series commercial “My Deciding Factor,” the ad highlights Sedes High’s strength: it contains the same active ingredients in the same amounts as prescription pain relievers.
Featuring Haruna Kawaguchi, her poised, confident delivery suggests you can expect strong effectiveness.
Shionogi Healthcare New SEDES Tablets: “Watch Out for Throbbing and Mizuki” VersionMizuki Yamamoto, Mio Imada
This is a Sedes commercial featuring Zukizuki Mizuki, played by Mizuki Yamamoto.
Although Zukizuki Mizuki is portrayed as a devil representing the cause of pain, fans of Yamamoto have also called her an “angel!” The way she says “Zuki zuki zuki~” is adorable.
The junior colleague appearing alongside Mizuki Yamamoto is the rising actress Mio Imada.
Shionogi Healthcare Sedes: ‘Fast relief for pain. Sedes High Series’ / ‘The pain professionals. Sedes brand’Haruna Kawaguchi
This is a commercial featuring Haruna Kawaguchi introducing the effectiveness of the Sedes High series.
The standout point is its fantastical world, whose grand and powerful atmosphere conveys both the high efficacy of Sedes and its reliability.
The way the background gradually brightens seems to suggest an image of pain being relieved and one’s field of vision opening up.
Shionogi Healthcare “SEDES High TV Commercial”Mizuki Yamamoto
This commercial features Mizuki Yamamoto dressed in a silver dress.
It’s crafted like footage from a fashion shoot, letting you fully appreciate her charm as a fashion model.
Not only is she beautiful, but the way she strikes confident poses is likely very appealing even from a woman’s perspective.
The familiar sound logo has also been stylishly rearranged.
Shionogi Healthcare New Sedes Tablets: “Dress” VersionMizuki Yamamoto
In this Cedes commercial featuring fashion model Mizuki Yamamoto, she shows off a glamorous model walk wearing a blue dress—the package color of Cedes.
Accompanied by light, rhythmic background music reminiscent of a fashion show, the direction clearly targets young women.
It concludes by displaying a logo and tagline designed to evoke a fashion magazine.
Shionogi Healthcare SEDES High Protect 2022 TV CommercialMizuki Yamamoto
Mizuki Yamamoto appeared in the 2022 commercial for Sedes High Protect.
In it, Yamamoto speaks for those who think, “I want a painkiller that works well, but I’m worried about the impact on my stomach,” and introduces Sedes High Protect.
The ad highlights that, with five active ingredients, it offers a friendly approach to headaches while also being gentle on the stomach.
Shionogi Healthcare New Sedes “Alien Appearance” VersionMizuki Yamamoto
In the 2022 commercial for New Sedes featuring Mizuki Yamamoto, it emphasizes that Sedes is a pain reliever that’s easy for anyone to use.
It carefully introduces each feature, such as the easy-to-open packaging and a QR code linking to a translated page that overseas users can understand.
It’s a commercial that really conveys how safe and reliable it is to use.